• J. Infect. Dis. · Jun 1990

    Case Reports

    Pertussis in an adult man infected with the human immunodeficiency virus.

    • B N Doebbeling, M L Feilmeier, and L A Herwaldt.
    • Department of Medicine, University of Iowa, Iowa City 52242.
    • J. Infect. Dis. 1990 Jun 1; 161 (6): 1296-8.

    AbstractA 25-year-old man infected with the human immunodeficiency virus (HIV) presented with paroxysmal cough and dyspnea of 4-months duration. An extensive evaluation including bronchoscopy was negative. A nasopharyngeal swab was positive by direct fluorescent antigen detection and culture for Bordetella pertussis. Respiratory isolation, treatment with erythromycin, and prophylaxis of household contacts was used to eradicate the organism and prevent transmission. Pertussis should be considered as a cause of prolonged cough and dyspnea in patients with HIV infection. The course of this patient was consistent with the concept that cell-mediated immunity is necessary for elimination of B. pertussis.

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