• Mol Pain · Jan 2020

    Review

    Role of fragile X mental retardation protein in chronic pain.

    • Xiangyang Mei, Yixin Yang, Jinsong Zhao, Yongjie Wang, QiLiang Chen, Xiang Qian, Xiangyao Li, and Zhiying Feng.
    • Department of Pain Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
    • Mol Pain. 2020 Jan 1; 16: 17448069209286191744806920928619.

    AbstractChronic pain has detrimental effects on one's quality of life. However, its treatment options are very limited, and its underlying pathogenesis remains unclear. Recent research has suggested that fragile X mental retardation protein is involved in the development of chronic pain, making it a potential target for prevention and treatment. The current review of literature will examine the function of fragile X mental retardation protein and its associated pathways, through which we hope to gain insight into how fragile X mental retardation protein may contribute to nociceptive sensitization and chronic pain.

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