• Vincenzo Tammaro, Nicola Carlomagno, Michele Santangelo, Armando Calogero, Concetta A Dodaro, Antonio Vernillo, Antonello Sica, Gaia Peluso, Silvia Campanile, Evangelista Sagnelli, and Caterina Sagnelli.
• Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy - vincenzo.tammaro@unina.it.
• Minerva Med. 2022 Oct 1; 113 (5): 846852846-852.

BackgroundMore than 50% of patients with colorectal cancer (CRC) present or develop hepatic metastases (HM). The intraoperative use of the Habib 4X® radio frequency probe device is safe in resetting HM and allows a one-stage resection of both CRC and HM with a similar mortality rate than a two-stage surgical treatment.MethodsAfter an exhaustive residential training at the reference center for hepato-biliary surgery of the Imperial College of London, we treated at our unit of general surgery 40 consecutive patients with CRC and HM with the one-stage resection, using the Habib 4X® intraoperative radiofrequency probe device to reset HM.ResultsNone of the 40 patients died during the intra-operatory and post-operatory periods, none presented liver failures during the postoperative course nor complication related to the Habib's resection procedure (e.g. bleeding, abscess, bile leak). The amount of intra-operative liver bleeding was minimal. New HM arose in 10 (25%) cases, with a mean disease-free interval of 13 months, but the hepatic tissue close to previous resections remained cancer-free. The 69.7% of patients were disease-free at month 24 of the post-operative follow-up and 5-year rate was about 70%.ConclusionsThe data suggest that surgeons well trained at a reference center for hepato-biliary surgery may perform with excellent results the one-stage CRC and HM resection with the Habib 4X® device even in a Unit of general surgery.

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