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Revista clínica española · Jun 2020
ReviewWhen does diabetes start? Early detection and intervention in type2 diabetes mellitus.
- F Gómez-Peralta, C Abreu, X Cos, and R Gómez-Huelgas.
- Unidad de Endocrinología y Nutrición, Hospital General de Segovia, Segovia, España. Electronic address: fgomezperalta@gmail.com.
- Rev Clin Esp. 2020 Jun 1; 220 (5): 305-314.
AbstractType 2 diabetes mellitus (DM2) is a progressive disease whose pathophysiological changes occur several years before its detection. An approach based on the pathophysiological development of DM2 and its complications emphasises the importance of early and intensive intervention, not only to prevent beta-cell dysfunction but also to act on the potential associated cardiovascular risk factors before reaching the blood glucose thresholds currently set for diagnosing DM2. In the field of recently diagnosed DM2, the VERIFY study has shown that early treatment combined with metformin-vildagliptin provides relevant improvements in long-term glycaemic control and can positively affect the disease's progression.Copyright © 2020 Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI). All rights reserved.
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