• Lam Carolyn S P CSP National Heart Centre Singapore and Duke-National University of Singapore, Singapore. , Yi-Heng Li, Antoni Bayes-Genis, Aekarach Ariyachaipanich, Do Quang Huan, Naoki Sato, Pravin Kahale, Ta Manh Cuong, Yugang Dong, Xinli Li, and Yanli Zhou.
• National Heart Centre Singapore and Duke-National University of Singapore, Singapore.
• J Chin Med Assoc. 2019 Jun 1; 82 (6): 447-451.

AbstractHeart failure (HF) is a growing challenge in the Asia Pacific region. N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a well-established tool for diagnosis of HF; however, it is relatively underutilized in predicting adverse outcomes in HF. Multiple studies have demonstrated the prognostic role of NT-proBNP in HF. A single value of NT-proBNP >5000 pg/mL predicts a worse outcome in hospitalized patients with HF with reduced ejection fraction (HFrEF). In stable outpatients with HFrEF, NT-proBNP > 1000 pg/mL predicts a poorer prognosis. NT-proBNP provides the same prognostic information in patients with HF with preserved ejection fraction (HFpEF) as in those with HFrEF. An expert panel composed of cardiologists mainly from Asia Pacific region was convened to discuss the utility of NT-proBNP in HF prognostication. This article summarizes available scientific evidence and consensus recommendations from the meeting.

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