• Der Internist · Aug 2020

    Case Reports

    [Proximal myopathy and fulminant heart failure in a 57 year-old female patient with lupus erythematosus].

    • F Wille, S Birkmeier, K Tiemann, T Lewalter, K Klingel, C Rabe, and P Sick.
    • Klinik für Innere Medizin I, Klinikum Dritter Orden, Menzinger Str. 44, 80638, München, Deutschland. florian.wille@posteo.de.
    • Internist (Berl). 2020 Aug 1; 61 (8): 854-859.

    AbstractA case report is presented of fulminant hydroxychloroquine-induced cardiomyopathy in a 57 year-old female patient with a long history of systemic lupus erythematosus. Diagnosis was established based on clinical findings, imaging (echocardiography and cardiac magnetic resonance imaging) as well as endomyocardial biopsy. Despite immediate discontinuation of the medication, the patient died from heart failure within a few days. Since the rare adverse effect described here might be reversible, early diagnosis and discontinuation of hydroxychloroquine are crucial for the prognosis of these patients.

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