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- William H Bermingham, Thomas Wilding, Sarah Beck, and Aarnoud Huissoon.
- University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK william.bermingham@nhs.net.
- Clin Med (Lond). 2020 Jul 1; 20 (4): 365368365-368.
AbstractSARS-CoV-2 serological tests are a subject of intense interest and have the potential to significantly enhance the diagnostic capability of healthcare services in the current pandemic. However, as with all novel assays, significant validation is required to understand the clinical relevance of results. We present the first study to assess clinician interpretation of SARS-CoV-2 serology scenarios. We identify common key assumptions regarding patient infectivity and protection that are not currently supported by the SARS-CoV-2 evidence base. In this rapidly developing field, we therefore strongly recommend serological assay results are accompanied by clear interpretive support from laboratory and infectious diseases specialists.© Royal College of Physicians 2020. All rights reserved.
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