• Diabetes Metab Syndr · Jul 2020

    Review

    SARS-CoV-2 infection and glucose homeostasis in pregnancy. What about antenatal corticosteroids?

    • Ioannis Kakoulidis, Ioannis Ilias, and Eftychia Koukkou.
    • Department of Endocrinology, Diabetes and Metabolism, Elena Venizelou General and Maternity Hospital, Athens, GR11521, Greece.
    • Diabetes Metab Syndr. 2020 Jul 1; 14 (4): 519-520.

    Background And AimsAdministration of corticosteroids is common in obstetric practice. In this concise review we queried on the effects of corticosteroids in pregnancies complicated by SARS-CoV-2.MethodsWe performed a literature search on PubMed, regarding the use of corticosteroids in patients with SARS-CoV-2 infection, in pregnancies complicated by SARS-CoV-2, as well as their impact on glycemia in pregnant women with or without diabetes. Furthermore, we searched for effects of SARS-CoV-2 and of other coronaviridae on insulin secretion and glycemia.ResultsSARS-CoV-2 infection appears to be a risk factor for complications in pregnancy. Corticosteroids may not be recommended for treating SARS-CoV-2 pneumonia but they may be needed for at-risk pregnancies. Corticosteroids in pregnancy have a diabetogenic potential. SARS-CoV-2 and other coronaviridae may have effects on glycemia.ConclusionsCaution should be exercised while using corticosteroids in pregnant women with COVID-19 requiring preterm delivery.Copyright © 2020 Diabetes India. Published by Elsevier Ltd. All rights reserved.

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