• Travel Med Infect Dis · Sep 2020

    Letter

    Detection and analysis of nucleic acid in various biological samples of COVID-19 patients.

    • Jianguo Wu, Jiasheng Liu, Shijun Li, Zhiyang Peng, Zhe Xiao, Xufeng Wang, Ruicheng Yan, and Jianfei Luo.
    • Department of Infection Disease Ward Five, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei province, China; Department of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei province, China. Electronic address: sangui2020@hotmail.com.
    • Travel Med Infect Dis. 2020 Sep 1; 37: 101673.

    AbstractCOVID-19 (corona virus disease 2019) is a kind of acute severe pneumonia caused by 2019-nCoV (2019-nCoV) infection. Since December 2019, it has been found in Wuhan, Hubei Province, and then spread to the whole country. Some parts of the world also showed an outbreak trend [1-3]. Real-time fluorescence quantitative reverse transcriptase polymerase chain reaction (reverse transcriptase-polymerase chain reaction,RT-PCR) and viral gene sequencing are the gold standard for the diagnosis of COVID-19. At present, upper respiratory tract nasopharyngeal swabs are mostly used as nucleic acid detection samples in China, but the positive rate is low. However, there are few reports on clinical application of 2019-nCoV nucleic acid detection in other biological samples.© 2020 Elsevier Ltd. All rights reserved.

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