• Internal medicine · Jan 2020

    Case Reports

    An HIV-infected Patient with No Serious Adverse Events after Overdosing on Raltegravir.

    • Tomohiro Hosoda, Yuki Uehara, and Toshio Naito.
    • Department of General Medicine, Juntendo University School of Medicine, Japan.
    • Intern. Med. 2020 Jan 15; 59 (2): 285-287.

    AbstractPatients with HIV infection represent a high-risk group for medication overdose because of the high frequency of complicating psychiatric disorders. Raltegravir is well-known for its low frequency of adverse effects. We herein report a 42-year-old Japanese man with HIV infection who was hospitalized 6 hours after overdosing with 24,000 mg of raltegravir in a suicide attempt. No serious adverse events occurred, although the plasma concentration of raltegravir at 18 hours after the overdose was 79,871.1 ng/mL. Raltegravir may be well-indicated for HIV patients at risk of overdosing.

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