• Paediatric anaesthesia · Aug 2020

    Multicenter Study Observational Study

    Ventilation in pediatric anesthesia: A French multicenter prospective observational study (PEDIAVENT).

    • Marion Lebossé, Delphine Kern, Mathilde De Queiroz, Nathalie Bourdaud, Francis Veyckemans, Dominique Chassard, Florent Baudin, and ADARPEF (Association Des Anesthésistes Réanimateurs Pédiatriques d'Expression Française).
    • Département d'Anesthésie-Réanimation, Hospices Civils de Lyon, Hôpital Femme Mère Enfant, Bron, France.
    • Paediatr Anaesth. 2020 Aug 1; 30 (8): 912-921.

    IntroductionProtective ventilation is now a standard of care in adults. However, management of ventilation is heterogeneous in children and little is known regarding the mechanical ventilation parameters actually used during pediatric anesthesia.AimThe aim of the study was to assess current ventilatory practices during pediatric anesthesia in France and to compare them with pediatric experts' statements, with a specific focus on tidal volume.Patients And MethodsWe conducted a prospective multicenter observational study, regarding the ventilatory management and the mechanical ventilation parameters, over two days (21 and 22 June 2017) in 29 pediatric centers in France. All children undergoing general anesthesia during these 2 days were eligible; those who required extracorporeal circulation or one-lung ventilation were excluded.ResultsA total of 701 children were included; median [IQR] age was 60 [24-120] months. Among the patients in whom controlled ventilation was used, 254/515 (49.3%) had an expired tidal volume >8 mL/kg and 44 children (8.8%) an expired tidal volume ≥10 mL/kg. Lower weight and use of a supraglottic airway device were significantly associated with provision of a tidal volume ≥10 mL/kg (odds ratio 0.94, 95% confidence interval [0.92; 0.97], P < .001 and 2.28 [1.20; 4.31], P = .012, respectively). The positive end-expiratory pressure was set at a median [IQR] of 4 [3-5] cmH2 O; it was <3 cmH2 O in 15.7% of children and not used in 56/499 (9.3%). Among intubated children, 57 (18.3%) received a tidal volume < 10 mL/kg with a positive end-expiratory pressure ≥3 cmH2 O in association with recruitment maneuvers.ConclusionsVentilatory practices in children were heterogenous, and a large proportion of children were not ventilated as it is currently recommended by some experts.© 2020 John Wiley & Sons Ltd.

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