• J. Thromb. Haemost. · Apr 2018

    Randomized Controlled Trial

    Aspirin withdrawal in patients treated with ticagrelor presenting with non-ST elevation myocardial infarction.

    • R Beigel, I Mazin, E Koifman, M Shechter, H Pres, N Shlomo, N Rosenberg, E Asher, and S Matetzky.
    • Cardiovascular Division, Intensive Cardiac Care Unit, Sheba Medical Center, Tel Aviv, Israel.
    • J. Thromb. Haemost. 2018 Apr 1; 16 (4): 663-669.

    AbstractEssentials Strong P2Y12 blockade may cause platelet inhibition that is only minimally enhanced by aspirin. We evaluated aspirin withdrawal on platelet reactivity in ticagrelor treated patients. Aspirin withdrawal resulted in increased platelet reactivity to arachidonic acid. Aspirin withdrawal caused little difference in adenosine diphosphate-induced platelet aggregation.© 2018 International Society on Thrombosis and Haemostasis.

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