• Med. Clin. North Am. · Jul 2020

    Review

    Sepsis and Septic Shock - Basics of diagnosis, pathophysiology and clinical decision making.

    • Michael D Font, Braghadheeswar Thyagarajan, and Ashish K Khanna.
    • Department of Anesthesiology, Wake Forest School of Medicine, Wake Forest Baptist Medical Center, 1, Medical Center Boulevard, Winston-Salem, NC 27157, USA.
    • Med. Clin. North Am. 2020 Jul 1; 104 (4): 573-585.

    AbstractSepsis and septic shock are major causes of mortality among hospitalized patients. The sepsis state is due to dysregulated host response to infection, leading to inflammatory damage to nearly every organ system. Early recognition of sepsis and appropriate treatment with antibiotics, fluids, and vasopressors is essential to reducing organ system injury and mortality. This review summarizes the current understanding of the epidemiology, pathophysiology, diagnosis, and treatment of sepsis and septic shock.Copyright © 2020 Elsevier Inc. All rights reserved.

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