• Journal of critical care · Oct 2020

    Case Reports

    Clinically significant anticardiolipin antibodies associated with COVID-19.

    • Sami Hossri, Mahmoud Shadi, Zaid Hamarsha, Rick Schneider, and Dany El-Sayegh.
    • Department of Pulmonary and Critical Care Medicine, Staten Island University Hospital, Staten Island, NY - Northwell Health, United States of America.
    • J Crit Care. 2020 Oct 1; 59: 32-34.

    AbstractThe novel coronavirus strain known as SARS-CoV-2 has rapidly spread around the world creating distinct challenges to the healthcare workforce. Coagulopathy contributing to significant morbidity in critically ill patients with SARS-CoV-2 has now been well documented. We discuss two cases selected from patients requiring critical care in April 2020 in New York City with a unique clinical course. Both cases reveal significant thrombotic events noted on imaging during their hospital course. Obtaining serial inflammatory markers in conjunction with anti-phospholipid antibody testing revealed clinically significant Antiphospholipid syndrome (APS). This case series reviews the details preceding APS observed in SARS-CoV-2 and aims to report findings that could potentially further our understanding of the disease.Copyright © 2020 Elsevier Inc. All rights reserved.

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