• Simone Bonatto, Vera Maria Vieira Paniz, Clandio de Freitas Dutra, and Ruth Liane Henn.
• . Área do Conhecimento de Ciências da Vida: Universidade de Caxias do Sul, Caxias do Sul, RS, Brasil.
• Rev Assoc Med Bras (1992). 2020 Mar 1; 66 (3): 268-274.

ObjectiveTo investigate the association between low serum vitamin D levels and peripheral arterial disease (PAD).MethodsA cross-sectional study with a consecutive sample of 133 individuals from Caxias do Sul, Brasil. We considered PAD patients those with an ankle-brachial index (ABI) ≤ 0.90 or with arterial revascularization. Vitamin D serum level was categorized as sufficient (≥30 ng/mL), insufficient (>20 to 29 ng/mL), and deficient (<20 ng/mL). Prevalence ratios (RP) were calculated through Poisson regression.ResultsThe prevalence of PAD was 50.7% (95% CI 42-59). After adjustment for potential PAD risk factors, RP were 1.08 (95% CI 0.66-1.76) for insufficient serum level and 1.57 (95% CI 0.96-2.57) for deficient vitamin D serum level; (p for trend = 0.020).ConclusionVitamin D serum levels showed an inverse and significant dose-response relationship with PAD.

23 keywords...

hide…