• Rev Assoc Med Bras (1992) · Mar 2020

    Analysis of the chemerin and resistin adipokines in children and adolescents.

    • Vanessa S Fontes, Kácia Mateus, Michele P Netto, Oliveira Renata M S RMS http://orcid.org/0000-0002-0274-6602 . Docente, Departamento de Nutrição, Instituto de Ciências Biológicas, Universidade Feder, George L L Machado-Coelho, and Cândido Ana Paula C APC http://orcid.org/0000-0002-1481-5927 . Docente, Departamento de Nutrição, Instituto de Ciências Biológicas, Universidade Feder.
    • .Doutoranda em Saúde Coletiva, Departamento de Nutrição, Instituto de Ciências Biológicas, Universidade Federal de Juiz de Fora, Juiz de Fora, MG, Brasil.
    • Rev Assoc Med Bras (1992). 2020 Mar 1; 66 (3): 300-306.

    ObjectivesTo compare the serum concentrations of adipokines resistin and chemerin in children and adolescents with eutrophic and overweight and to evaluate their relationship with anthropometric, biochemical, and blood pressure variables.Methodsa cross-sectional epidemiological study was conducted with 234 students enrolled in public elementary schools in the city of Juiz de Fora / MG. Anthropometric evaluation, biochemistry, and blood pressure measurement were performed. Statistical analyzes included the Student-t or Mann-Whitney tests, Pearson or Spearman correlation, used according to the distribution of the variables, and linear regression analysis, by means of the evaluation of the effect of the independent variables on the serum levels of chemerin and resistin, adjusted for age and sex. For the data analysis, SPSS® software version 21.0 and STATA® version 10.1 were used, assuming a significance level of 5%.Resultsthe concentrations of chemerin were higher in eutrophic individuals than in those with excess weight (p> 0.05). In contrast, levels of resistin were higher in the young with excess weight than in the eutrophic ones (p <0.05). In the multiple linear regression analysis, the levels of chemerin were associated with the values of resistin, systolic, and diastolic blood pressure. Resistance levels maintained association only with BMI and chemerin values.Conclusionthe adipokines analyzed presented a distinct profile in the groups of children and adolescents with eutrophic and overweight.

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