• Presse Med · Apr 2020

    Review Case Reports

    IgG4 hypophysitis: Diagnosis and management.

    • M Lojou, J F Bonneville, M Ebbo, N Schleinitz, and F Castinetti.
    • Inserm, U1251, CRMR HYPO, department of endocrinology, Aix-Marseille université, La Conception hospital, AP-HM, 147, boulevard Baille, Marseille, France.
    • Presse Med. 2020 Apr 1; 49 (1): 104016.

    AbstractIgG4-related hypophysitis is a rare disease, due to a lymphoplasmocytic IgG4 positive infiltration of the pituitary. Literature data are scarce, even though the description of cases has drastically increased over the last years. The aim of this review is to better characterize the natural history, the diagnosis and the management of IgG4-related hypophysitis, based on a clinical case, an exhaustive Pubmed research, and a reappraisal of the criteria for diagnosis. We will specifically focus on the differences with other etiologies of hypophysitis, in the aim of improving the diagnostic procedures for all the physicians who could have to take care of such patients.Copyright © 2020 Elsevier Masson SAS. All rights reserved.

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