• J J Hijona Elósegui, A L Carballo García, A C Fernández Risquez, M Bermúdez Quintana, and J F Expósito Montes.
• Servicio de Obstetricia y Ginecología, Hospital Universitario materno-Infantil de Jaén, Jaén, España. Electronic address: jesushijona@gmail.com.
• Rev Clin Esp. 2021 Feb 1; 221 (2): 939693-96.

Background And ObjectiveOn January 7th, 2020, a new coronavirus, SARS-CoV-2, was identified, as responsible for a new human disease: COVID-19. Given its recent appearance, our current knowledge about the possible influence that this disease can exert on pregnancy is very limited. One of the unknowns to be solved is whether there is a vertical transmission of the infection during pregnancy.Patients And MethodsUsing the Real-time Polymerase Chain Reaction techniques for SARS-CoV-2 nucleic acids, the possible presence of this germ in vaginal discharge and amniotic fluid was investigated in four pregnant Caucasian patients affected by mild acute symptoms of COVID-19 during the second trimester of pregnancy.ResultsThere is no laboratory evidence to suggest a possible passage of SARS-CoV-2 from the infected mother to the amniotic fluid.ConclusionsIt is necessary to expand the investigation of COVID-19 cases diagnosed during pregnancy to clarify the real influence that SARS-CoV-2 has on pregnant women and their offspring, as well as those factors that modulate the disease.Copyright © 2020 Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI). All rights reserved.

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