• Arian Zaboli, Dietmar Ausserhofer, Norbert Pfeifer, Pasquale Solazzo, Gabriele Magnarelli, Marianne Siller, and Gianni Turcato.
• Emergency Department, Hospital of Merano (SABES-ASDAA), Merano-Meran, Italy. Electronic address: zaboliarian@gmail.com.
• J Crit Care. 2020 Oct 1; 59: 63-69.

ObjectiveUp to 15% of patients arrive in the emergency department suffering from fever. Triage is their first contact and is responsible for the stratification of patients according to the severity of the condition for which they are presenting at the emergency department. The aim of this study is to assess the predictive validity of the Manchester Triage System in patients with fever for sepsis or septic shock and seven-day mortality.MethodsThe sensitivity, specificity and negative predictive value of the Manchester Triage System was assessed by priority code allocation towards seven-day mortality and the diagnosis of sepsis or septic shock.ResultsA total of 3831 patients were evaluated in the emergency department for fever between 1 January 2017 and 30 June 2019. Of these, 1.9% were diagnosed with sepsis or septic shock. Using the Manchester Triage System to predict diagnosis of sepsis or septic shock provided a sensitivity of 88.7%, a specificity of 50.1% and a negative predictive value of 99.5%. For seven-day mortality, sensitivity was 44.4%, specificity was 92.3% and the negative predictive value was 99.3%.ConclusionThe Manchester Triage System has demonstrated high sensitivity and negative predictive value in patients with fever diagnosed with sepsis or septic shock. For patients with sepsis or septic shock one-third of cases with an incorrectly assigned priority code were caused by incorrect application of the Manchester Triage System.Copyright © 2020 Elsevier Inc. All rights reserved.

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