• Arch. Bronconeumol. · Nov 2013

    Multicenter Study

    Comorbidities and health status in individuals with and without COPD in five Latin American cities: the PLATINO study.

    • Maria Victorina López Varela, María Montes de Oca, Ronald Halbert, Adriana Muiño, Carlos Tálamo, Rogelio Pérez-Padilla, José Roberto B Jardim, Gonzalo Valdivia, Julio Pertuzé, Ana María B Menezes, and PLATINO team.
    • Servicio de Neumología, Hospital Maciel, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay. Electronic address: mlopez@chasque.net.
    • Arch. Bronconeumol. 2013 Nov 1; 49 (11): 468-74.

    IntroductionComorbidities are common in patients with chronic obstructive pulmonary disease (COPD), and have a significant impact on health status and prognosis. The PLATINO study provides data on self-reported comorbidities and perceived health status in COPD subjects.MethodsPLATINO is a population-based study on COPD prevalence in five Latin American cities. COPD diagnosis was defined by GOLD criteria (FEV1/FVC<.70 post-bronchodilator). Information was collected on the following comorbidities: heart disease, hypertension, diabetes, cerebrovascular disease, peptic ulcer and asthma. Health status was evaluated using the SF-12 questionnaire, derived from the question: «In general, would you say your health is excellent, very good, good, fair or poor?». A simple comorbidity score was calculated by adding the total number of comorbid conditions.ResultsOf a total population of 5314individuals, 759 had COPD. Reported comorbidities by decreasing frequency were: any cardiovascular disease, hypertension, peptic ulcer, heart disease, diabetes, cerebrovascular disease, asthma and lung cancer. COPD patients had a higher comorbidity score and prevalence of lung cancer (P<.0001) and asthma (P<.0001), as well as a higher tendency to have hypertension (P=.0652) and cerebrovascular disease (P=.0750). Factors associated with comorbidities were age, body mass index (BMI) and female gender. The number of comorbidities increased as the health status deteriorated.ConclusionsIn the PLATINO population-based study, COPD individuals had an increased number of comorbidities. Age, female gender and higher BMI were the factors associated with comorbidity in these patients. Comorbid conditions were associated with impaired health status, independently of the COPD status.Copyright © 2013 SEPAR. Published by Elsevier Espana. All rights reserved.

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