• Internal medicine journal · Jun 2020

    Review

    Hyponatraemia in heart failure.

    • Su Ling Tee, Andrew Sindone, Simon Roger, John Atherton, John Amerena, Michael D'Emden, Jonathan Erlich, and Carmine De Pasquale.
    • Department of Cardiology, The Alfred, Melbourne, Victoria, Australia.
    • Intern Med J. 2020 Jun 1; 50 (6): 659-666.

    AbstractHyponatraemia is common in heart failure (HF). It is estimated that over 20% of patients admitted to hospital with HF have hyponatraemia. It has also been repeatedly shown to be a surrogate marker of increased morbidity and mortality in this specific population. This review focuses on the pathophysiology of hyponatraemia through the activation of neurohormonal cascades in HF, the clinical implications of sustained hyponatraemia and treatment options in the management of this challenging phenomenon.© 2019 Royal Australasian College of Physicians.

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