• Shan Hu, Yeqing Gu, Zuolin Lu, Qing Zhang, Li Liu, Ge Meng, Zhanxin Yao, Hongmei Wu, Xue Bao, Vu Thi Quynh Chi, Shunming Zhang, Mingyue Liu, Yanyan Wang, Liu Wang, Lixiao Zheng, Xiaona Wang, Chunling Tian, Jingzhu Fu, Shaomei Sun, Ming Zhou, Qiyu Jia, Kun Song, Zhong Sun, and Kaijun Niu.
• Nutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
• Am J Prev Med. 2019 Jun 1; 56 (6): 844-851.

IntroductionPrediabetes has been a growing health problem in China, and it is a high-risk state for developing diabetes and cardiovascular disease. In previous studies, low grip strength has been associated with diabetes. However, few population-based studies have examined the relationship between grip strength and prediabetes. Thus, the purpose of this study was to investigate whether grip strength is related to prediabetes in a large-scale adult population.MethodsA total of 27,295 participants aged 20 to 90 years were included from the 2013-2016 Tianjin Chronic Low-grade Systemic Inflammation and Health Cohort Study. Grip strength was assessed using an electronic hand-grip dynamometer and the greatest force was normalized to body weight. Prediabetes was diagnosed based on the American Diabetes Association criteria. Multiple logistic regression analysis was conducted in 2018 to assess the relationship of grip strength to the prevalence of prediabetes, while controlling for age, BMI, smoking, drinking, physical activities, dietary patterns, and other confounders.ResultsOf the 27,295 participants, 28.5% (7,783) had prediabetes. After adjusting for potential confounders, a one unit increase in grip strength per body weight was associated with 52% lower odds of having prediabetes for men (OR=0.48, 95% CI=0.30, 0.74, p<0.01) and 62% lower odds of having prediabetes for women (OR=0.38, 95% CI=0.20, 0.70, p<0.01).ConclusionsIncreased grip strength is independently associated with lower prevalence of prediabetes in Chinese adults, suggesting that grip strength may be a useful marker for screening individuals at risk of prediabetes.Copyright © 2019 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

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