• Andrew Clark, Kate Lloyd, Aziz Sheikh, Mazin Alfaham, Mandy East, Pamela Ewan, Fiona Jewkes, Rosie King, Susan Leech, Ian Maconochie, Louise Sinnott, Dalbir Sohi, Stephen Tomlin, John Warner, and Science and Research Department, Royal College of Paediatrics and Child Health.
• Department of Allergy, Addenbrooke's NHS Trust, Box 40, Cambridge CB2 0QQ, UK. atclark@doctors.org.uk
• Arch. Dis. Child. 2011 Nov 1; 96 Suppl 2: i6-9.

AimsNumerous studies have identified shortcomings in the management of children at risk of severe acute allergic reactions (anaphylaxis). The Science and Research Department at the Royal College of Paediatrics and Child Health (RCPCH) was commissioned by the Department of Health to develop competence based national care pathways for children with allergies. Anaphylaxis is the first completed pathway.MethodsThe anaphylaxis pathway was developed by a multidisciplinary working group, reviewed by a broad group of stakeholders and approved by the Allergy Care Pathways Project Board and the RCPCH Clinical Standards Committee.ResultsPathway development is described under five headings: evidence review, mapping, external review, core knowledge documents and key recommendations. The full pathway can be downloaded from www.rcpch.ac.uk/allergy/anaphylaxis. This document describes the entry points and the ideal pathway of care from self-care through to follow-up. The five key recommendations focus on: (1) prompt administration of adrenaline by intramuscular injection; (2) referral to specialists with competence in paediatric allergies; (3) risk analysis; (4) provision of a self-management plan; and (5) suggested creation of a national anaphylaxis death register.ConclusionsWe present the first national care pathway for anaphylaxis, which is based on a critique of published evidence, expert consensus and multi-stakeholder input including patient representation via the Anaphylaxis Campaign. The Project Board urges health professionals to work together across networks to improve care for children at risk of anaphylaxis, in particular during the period after an acute reaction. Additionally, the Project Board strongly recommends the funding of a national anaphylaxis register.

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