• Int. J. Clin. Pract. · Oct 2020

    Prognostic Factors for Surgical Margin Status and Recurrence in Partial Nephrectomy.

    • Hüseyin C Demirel, Sedat Çakmak, Abdullah H Yavuzsan, Cumhur Yeşildal, Semih Türk, Ayhan Dalkılınç, Sinan L Kireççi, Emre Tokuç, and Kaya Horasanlı.
    • Department of Urology, Sisli Hamidiye Etfal Training & Research Hospital, Medical Sciences University, Istanbul, Turkey.
    • Int. J. Clin. Pract. 2020 Oct 1; 74 (10): e13587.

    PurposeTo evaluate the prognostic factors affecting the surgical margin and recurrence in patients who underwent partial nephrectomy (PN) for renal masses.Materials And MethodsData of 125 patients who underwent open or laparoscopic PN because of renal mass between January 2006 and January 2019 were analysed retrospectively. Demographic data, habits, additional diseases, clinical and laboratory findings, operational data, the morphology of the tumour in computerised tomography or magnetic-resonance imaging and follow-up data were scanned and acquired via our hospital's system and archive.ResultsAverage age was 54.4, male-female ratio was 1.55 and average tumour size was 3.31 cm. One hundred and four patients had malignant pathology and 21 were benign. Positive surgical margin (PSM) rate was 5.6% and recurrence rate was 3.2%. Average follow-up was 47.4 months. Pathological size of the tumour was larger (P = .006), warm-ischemia period was lower (P = .003) and PADUA score was higher (P = .015) in open technique. Tumour size and tumour stage were statistically higher in patients with recurrence (P = .009, P < .001, respectively). There was a significantly higher PSM ratio in mandatory indication group than elective indication group (P = .025). No statistically significant difference was observed between surgical margin positivity and tumour size, Fuhrman grades, PADUA scores, RENAL scores and C-index. (P > .05).ConclusionSurgical margin positivity after PN is not significantly associated with tumour characteristics and anatomical scoring systems. Surgical indication for PN has a direct influence on PSM rates. Tumour size and stage after PN are valuable parameters in evaluating the recurrence risk.© 2020 John Wiley & Sons Ltd.

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