• Dong Chen, Bo Yang, Yan Zhang, Liang Chen, Lai Wei, Weijie Zhang, Xinqiang Wang, Xiaolin Tong, and Zhishui Chen.
• Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan.
• Medicine (Baltimore). 2020 Jun 12; 99 (24): e20481e20481.

RationaleCoronavirus disease 2019 (COVID-19) is a novel infectious disease and became a global issue. Treatment of COVID-19 especially in solid organ transplant recipients is empirical and controversial, especially the adjustment of the immunosuppressants.Patient ConcernsA 29-year-old kidney transplant recipient with the symptoms of COVID-19 pneumonia.DiagnosesCOVID-19 pneumonia after kidney transplantation.InterventionsHe was treated with modified immunosuppressants (unchanged dose of tacrolimus and oral corticosteroids while discontinuing mycophenolate mofetil (MMF)), antibiotics, interferon α-2b inhalation and traditional Chinese medicine.OutcomesHe recovered from COVID-19 pneumonia after 29 days of hospitalization. And the renal function (measured as blood urea nitrogen, serum creatinine, and urine protein) returned to normal.LessonsIn certain group of COVID-19 (e.g., mild to moderate cases, young patients without comorbidities), a reduction instead of an overall withdrawal of immunosuppressant in kidney transplant recipients is feasible.

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