• J. Korean Med. Sci. · Jun 2020

    Case Reports

    A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance.

    • Byeong Yun Ahn, Chang Kyung Kang, Jong Do Seo, Pyoeng Gyun Choe, Sang Hoon Song, Wan Beom Park, Sang Won Park, Nam Joong Kim, and Myoung Don Oh.
    • Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
    • J. Korean Med. Sci. 2020 Jun 22; 35 (24): e231e231.

    AbstractThere have been controversies on the prophylactic effect of hydroxychloroquine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We describe a patient, 60-year old Korean woman, with coronavirus disease 2019 (COVID-19) who had been taking hydroxychloroquine for 6 months. Her serum and saliva concentrations of hydroxychloroquine were 280 μg/L and 4,890 μg/L, respectively. The present case raises concerns on hydroxychloroquine's role as a prophylactic agent for COVID-19.© 2020 The Korean Academy of Medical Sciences.

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