• P Constant Dit Beaufils, S De Gaalon, O Espitia, G Ploton, S Mercier, R Liberge, and J Connault.
• Clinique neurologique, CHU de Nantes, Boulevard Jacques Monod, 44093 Nantes cedex 1, France. Electronic address: pacome.constantditbeaufils@chu-nantes.fr.
• Rev Med Interne. 2020 Sep 1; 41 (9): 628-631.

IntroductionHereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease characterized by the triad of nose bleeding, telangiectasia and familial heredity.Case ReportWe report the case of a patient who had idiopathic venous cerebral thrombosis complicated by a cerebral infarction treated with warfarin. In the context of a psoas hematoma by warfarine overdose and immobilization, the patient had deep vein thrombosis of the left lower limb with pulmonary embolism revealing a pulmonary arteriovenous malformation. After a reexamination, the patient clinical phenotype of HHT was confirmed genetically. The patient was treated with rivaroxaban allowing clinical improvement and partial recanalization of all thrombosis after six months. Thrombotic overisk has already been studied in HHT patients but the use of anticoagulants is at higher risk in these patients. However this patient experienced no adverse event with rivaroxaban.ConclusionThis is the first case described of cerebral venous thrombosis treated with rivaroxaban revealing an HHT.Copyright © 2020. Published by Elsevier Masson SAS.

41 keywords...

hide…