• Juliana Ferreira Ferranti, Isadora Souza Rodriguez, Emiliana Motta, Cíntia Johnston, Werther Brunow de B Carvalho, and Artur Figueiredo Delgado.
• . Universidade de São Paulo Instituto da Criança, Unidade de Terapia Intensiva Pediátrica, São Paulo, SP, Brasil.
• Rev Assoc Med Bras (1992). 2020 Apr 1; 66 (4): 521-527.

AbstractSevere acute respiratory syndrome coronavirus 2 (Sars-CoV-2 infection) is a new challenge for all countries, and children are predisposed to acquire this disease. Some studies have demonstrated more severe diseases in adults, but critically ill pediatric patients have been described in all ages. Pulmonary involvement is the major feature, and ventilatory support is common in critical cases. Nevertheless, other very important therapeutic approaches must be considered. In this article, we reviewed extensively all recent medical literature to point out the main clinical attitudes to support these pediatric patients during their period in respiratory support. Radiologic findings, fluid therapy, hemodynamic support, use of inotropic/vasopressors, nutritional therapy, antiviral therapy, corticosteroids, antithrombotic therapy, and immunoglobulins are analyzed to guide all professionals during hospitalization. We emphasize the importance of a multi-professional approach for adequate recovery.

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