• Rev Assoc Med Bras (1992) · Apr 2020

    Review

    Sars-CoV-2: A clinical update - II.

    • Mateus da Silveira Cespedes and José Carlos Rosa Pires de Souza.
    • . Estudante de Medicina do Sexto Ano da Universidade Estadual do Mato Grosso do Sul, Campo Grande, MS, Brasil.
    • Rev Assoc Med Bras (1992). 2020 Apr 1; 66 (4): 547-557.

    IntroductionA covid-19 pandemic decreed by WHO has raised greater awareness of it.EpidemiologyThe infection, reached the mark of 2,000,000 patients in 33 countries and caused the risk of the presence of comorbidities and advanced age.TransmissibilityThe transmissibility calculated so far is similar to the H1N1 epidemic, but with lower mortality rates.PhysiopathologyThe SARS-CoV-2 virus, of the Coronaviridae family, has the capacity for cellular invasion through the angiotensin-converting enzyme 2 does not have a lower respiratory epithelium and in the cells of the small intestine mucosa.Clinical Manifestationsa presentation can be divided into mild (fever, fatigue, cough, myalgia, and sputum) and severe (cyanosis, dyspnoea, tachypnea, chest pain, hypoxemia and need for clinical measurement) and has an estimated estimate of 2%.Diagnosisallows the detection of viral load in CRP-TR of patients with high clinical suspicion.Treatmentbased on supportive measures and infection control. In severe cases, the use of medications such as hydroxychloroquine and azithromycin or medication can be promising. Take care to avoid the use of corticosteroids. There are no restrictions on the use of resources and IECAs / BRAs.

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