• Terapevt Arkh · Dec 2019

    [Clinical and economic analysis of Reslizumab use in the treatment of patients with severe allergic eosinophilic asthma].

    • A S Kolbin, S N Avdeev, M V Zhuravleva, Y M Gomon, Y E Balykina, N V Matveyev, M A Proskurin, and S V Fedosenko.
    • Pavlov First Saint Petersburg State Medical University.
    • Terapevt Arkh. 2019 Dec 15; 91 (12): 47-56.

    AbstractAsthma is a heterogeneous chronic disease of airways. One of its endotypes is eosinophilic asthma, accompanied by both peripheral blood and airway eosinophilia, where severe eosinophilia is usually associated with more severe asthma. Anti - interleukin-5 (IL-5) monoclonal antibodies (MAb) can reduce eosinophil counts in peripheral blood and tissues in asthma patients. The first drug of this class registered in Russia was reslizumab.

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