• Terapevt Arkh · Apr 2020

    [Hyperammonaemia in patients with chronic obstructive pulmonary disease and obesity: association mechanisms, detection rate and correction].

    • S A Kozhevnikova, L V Tribuntseva, and A V Budnevsky.
    • Burdenko Voronezh State Medical University.
    • Terapevt Arkh. 2020 Apr 27; 92 (2): 55-60.

    AbstractChronic obstructive pulmonary disease (COPD) is a world-wide problem. It is characterized by comorbidity. Among the numerous comorbidity obesity is considered. The common pathogenetic factors cause the more severe course of COPD. Obesity is a complex metabolic condition affecting many physiological systems, in particular, the metabolic liver affection is developing in the type of non-alcoholic liver disease. In patients with different stages of non-alcoholic liver disease detoxification function is reduced. Toxic ammonia does not convert in urea. Ammonia begins to affect the whole organism.

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