• Terapevt Arkh · Jul 2019

    [Somatic mutation of the V617F JAK2 gene in patients of the cardiovascular diseases].

    • I A Olkhovskiy, A S Gorbenko, M A Stolyar, D A Grischenko, O A Tkachenko, and T L Martsinkevich.
    • Krasnoyarsk branch of the «National Research Center for Hematology».
    • Terapevt Arkh. 2019 Jul 15; 91 (7): 25-28.

    AbstractThe JAK2 V617F somatic mutation is one of the most frequent markers of CHIP (clonal hematopoiesis of indeterminate potential). CHIP is characterized by the presence of a myeloid cells clone in peripheral blood in the absence of the sufficient reasons to diagnose the hematologic disease. The CHIP is proposed as a potential independent risk factor for vascular pathology. The aim of this study is to identify carriers of JAK2 V617F mutation among patients admitted for planned hospitalization at the Federal Center of Cardiovascular Surgery of Krasnoyarsk.

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