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- V I Podzolkov, T A Safronova, and D U Natkina.
- Sechenov First Moscow State Medical University (Sechenov University).
- Terapevt Arkh. 2019 Sep 15; 91 (9): 108-114.
AimTo conduct a comparative analysis of the level of asymmetric dimethylarginine (ADMA) in two groups of patients with a diagnosis of essential arterial hypertension (AH). Group I - patients with uncontrolled hypertension (UCAH) and group II - patients with controlled course of hypertension (CAH).Materials And MethodsThe study included 109 patients: group I - 73 patients with UCAH, group II - 36 patients with CAH. Groups were comparable. Clinical, laboratory and instrumental examination was performed, including determination of ADMA concentration in blood plasma.ResultsThe concentration of ADMA in patients with UCAH was significantly higher than in the group with CAH. In patients with UCAH, a pronounced positive correlation was found between the concentration of ADMA and creatinine level (r=0.615, p.
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