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- S N Batskikh, E V Vinnitskaya, Y G Sandler, and T Y Khaimenova.
- A.S. Loginov Moscow Clinical Scientific and Practical Center, Moscow City Department of Health.
- Terapevt Arkh. 2018 Nov 15; 90 (11): 67-73.
AbstractToday, there is no complete clarity about the pathogenetic mechanisms of the hepatic decompensation in patients with HCV-cirrhosis during the course of direct-acting antiviral (DAAs) therapy. The current article describes several clinical observations of decompensation (with the development of liver failure and portal hypertension) in cirrhotic patients during the course of DAAs-therapy of hepatitis C. The authors present contemporary views and their own assumptions about the possible mechanisms of the hepatic decompensation associated with DAAs-therapy in patients with liver cirrhosis.
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