• J Clin Neurosci · Jun 2019

    Case Reports

    A school-aged boy with super-refractory status epilepticus secondary to cortical dysplasia treated with dexmedetomidine.

    • John R Malta, Jonathan Greco, Mauro Lodolo, and Suman Ghosh.
    • University of Florida, Department of Pediatrics, Division of Neurology, 1600 SW Archer Road, Gainesville, FL 32608, United States. Electronic address: jmalta@ufl.edu.
    • J Clin Neurosci. 2019 Jun 1; 64: 21-22.

    AbstractThis case report details a novel approach to the management of super-refractory status epilepticus (SRSE) in a boy with new-onset seizures progressing to SRSE. After exhausting multiple medications, dexmedetomidine, an α2-adrenoreceptor agonist used for sedation, stopped his SRSE. Dexmedetomidine provides a unique mechanism of action to treat this condition. Further studies are needed to determine its role in SRSE.Published by Elsevier Ltd.

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