• Michele Correale, Natale Daniele Brunetti, Lucia Forte, Tommaso Passero, Ilenia Monaco, Armando Ferraretti, Antonio Totaro, Giovanna Elisiana Carpagnano, Foschino Barbaro Maria Pia MP Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy., Matteo Di Biase, and Donato Lacedonia.
• Cardiology Department, Ospedali Riuniti, Foggia, Italy.
• Eur. J. Clin. Invest. 2015 Nov 1; 45 (11): 1153-60.

BackgroundTissue Doppler imaging (TDI) is used to improve risk stratification in patients with chronic heart failure (CHF). So far, few studies have used this method to investigate the characteristics of subjects with CHF and Cheyne-Stokes breathing (CSB). The aim of this study was therefore to evaluate whether TDI assessment may predict the presence of CSB in patients with CHF.Materials And MethodsA total of 41 consecutive patients with CHF enrolled in the Daunia Heart Failure Registry underwent echocardiography assessment and nocturnal polygraphy to evaluate the presence of sleep apnea and CSB. Conventional echocardiography and TDI parameters were calculated. We have also quantified by TDI a combined index (EAS index) of diastolic and systolic performance: E'/(A' × S').ResultsSubjects with evidence of CSB (N = 8) were characterized by lower values of A' (5·03 ± 2·64 vs. 7·88 ± 2·64 cm/s, P < 0·01). A' and EAS index values were related to Cheyne-Stokes episode rates (r = -0·49 and 0·52, P < 0·05 and <0·01 respectively), EAS index values also with the number of episodes of central apnea (r = 0·39, P < 0·05). A' values predicted the presence of CSB at poly-somnography examination with an OR 0·62 (95% CI 0·40-0·96, P < 0·05) even after correction for age and gender.ConclusionsTissue Doppler imaging values (A') are associated with the presence of sleep apnea at nocturnal polygraphy.© 2015 Stichting European Society for Clinical Investigation Journal Foundation.

27 keywords...

hide…