• Satoshi Shimai, Kenjiro Yamamoto, Atsushi Sofuni, Takayoshi Tsuchiya, Kentaro Ishii, Reina Tanaka, Ryosuke Tonozuka, Mitsuyoshi Honjo, Shuntaro Mukai, Mitsuru Fujita, Kazumasa Nagai, Yasutsugu Asai, Yukitoshi Matsunami, Takashi Kurosawa, Hiroyuki Kojima, Hirotoshi Honma, Hiroto Minami, Hiroshi Yamaguchi, and Takao Itoi.
• Department of Gastroenterology and Hepatology, Tokyo Medical University, Japan.
• Intern. Med. 2020 Oct 1; 59 (19): 2369-2374.

AbstractWe herein report three cases of patients with an ampullary neuroendocrine tumor (NET), who underwent endoscopic papillectomy (EP). No tumor recurrence or metastasis was detected in the patients for more than two years after EP. Generally, surgical resection is recommended for ampullary NETs by the European Neuroendocrine Tumor Society. However, as EP is less invasive than surgical resection, there are some reports of low-grade small ampullary NETs curatively treated by EP with long-term follow-up. We consider that EP may be a curative treatment for small and low-grade ampullary NETs without regional or distant metastasis.

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