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- Yuhei Shiga, Yoshiaki Idemoto, Kohei Tashiro, Tomoki Imaizumi, Yoko Ueda, Yuiko Yano, Kenji Norimatsu, Ayumi Nakamura, and MiuraShin-IchiroSIDepartment of Cardiology, Fukuoka University School of Medicine, Japan..
- Department of Cardiology, Fukuoka University School of Medicine, Japan.
- Intern. Med. 2020 Oct 1; 59 (19): 239123952391-2395.
AbstractA 65-year-old man was followed for his coronary conditions using 320-multi detector row computed tomography (MDCT) for 30 months. He had soft plaque in the right coronary artery (RCA) [mean density of plaque was 22 hounsfield units (HU)]. His initial serum low-density lipoprotein cholesterol (LDL-C) was 72 mg/dL. After 30 months, his serum LDL-C was 26 mg/dL under 5.0 mg/day rosuvastatin and evolocumab 140 mg/2 weeks. MDCT showed a regression of the plaque in the RCA and the plaque density was 114 HU (intermediate plaque). In conclusion, intensive lipid-lowering therapy with evolocumab induced the regression and stabilization of coronary vulnerable plaque.
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