• Internal medicine · Oct 2020

    Case Reports

    Localized Lymph Node Light Chain Amyloidosis.

    • Akira Yamamoto, Nobuharu Fujii, Mikako Obika, Taro Yamashita, and Fumio Otsuka.
    • Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan.
    • Intern. Med. 2020 Oct 1; 59 (19): 2415-2418.

    AbstractThe prognosis of systemic amyloid light chain (AL) amyloidosis is generally poor, hence requiring chemotherapy or hematopoietic stem cell transplantation, while the prognosis of localized AL amyloidosis without an abnormal monoclonal immunoglobulin light chain is good. Localized AL amyloidosis has been previously reported to be observed in pulmonary, urinary tract, gastrointestinal, oropharyngeal, and laryngeal sites. However, only a few cases of localized lymph node AL amyloidosis have so far been reported. We herein present a case of localized lymph node AL amyloidosis that could possibly be misdiagnosed as systematic AL amyloidosis.

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