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Review Case Reports
A Long-term Survival Case of Pulmonary Tumor Thrombotic Microangiopathy due to Gastric Cancer Confirmed by the Early Diagnosis based on a Transbronchial Lung Biopsy.
- Takeshi Imakura, Toshifumi Tezuka, Mami Inayama, Ryota Miyamoto, Akane Abe, Kanako Otsuka, Seiji Yoshida, Eiji Kudo, and Takashi Haku.
- Department of Respiratory Medicine, Tokushima Prefectural Central Hospital, Japan.
- Intern. Med. 2020 Jan 1; 59 (13): 1621-1627.
AbstractPulmonary tumor thrombotic microangiopathy (PTTM) is an acute, progressive, and fatal disease. PTTM manifests as subacute respiratory failure with pulmonary hypertension, progressive right-sided heart failure, and sudden death. An antemortem diagnosis of PTTM is very difficult to obtain, and many patients die within several weeks. We herein report a case of PTTM diagnosed based on a transbronchial lung biopsy. In this case, we finally diagnosed PTTM due to gastric cancer because of its histological identity. The patient was administered chemotherapy, including angiogenesis inhibitors, against gastric cancer at an early age and survived for a long time.
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