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Historical Article
Practical implications of the 2019 Nobel Prize in Physiology or Medicine: from molecular adaptation to hypoxia to novel anti-anemic drugs in the clinic.
- Fabiana Busti, Giacomo Marchi, Alice Vianello, and Domenico Girelli.
- Department of Medicine, Section of Internal Medicine, EuroBloodNet Referral Center for Iron Metabolism Disorders, Azienda Ospedaliera Universitaria Integrata Verona, University of Verona, 37134, Verona, Italy. fabiana.busti@univr.it.
- Intern Emerg Med. 2020 Sep 1; 15 (6): 911-915.
AbstractThe 2019 Nobel Prize for Medicine or Physiology was assigned to three prestigious physician-scientists, Gregg L. Semenza, William G. Kaelin, and Peter J. Ratcliffe, who clarified the molecular mechanisms of hypoxia adaptation. This viewpoint traces their fundamental findings, which have paved the way for the development of innovative drugs for a wide range of common diseases, including cancer and anemia.
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