• Andrea Cossio, Jole Graci, Antonino Salvatore Lombardo, Marco Turati, Maria Luisa Melzi, Marco Bigoni, and Giovanni Zatti.
• Orthopedic Department, San Gerardo Hospital, University of Milano - Bicocca, Monza, Italy.
• Ital J Pediatr. 2019 Jul 26; 45 (1): 91.

BackgroundBrodie's abscess is a form of chronic pyogenic osteomyelitis that usually affects the cancellous part of the long bones in children. Its treatment is represented by antibiotic therapy alone or in association with surgical procedures.Case PresentationA 12-years-old male affected by a Brodie's abscess of the tibia involving the distal growth plate was admitted to the Pediatric Department for a conservative treatment. After several attempts of antibiotic therapy interrupted for intolerance manifestations he was surgically treated with bioactive glass BAG-S53P4 (BonAlive, BonAlive Biomaterials Ltd., Biolinja, Finland), with excellent results.ConclusionsIn our experience BAG-S53P4 has proven to be an effective bone substitute without side effects even in the pediatric population. In our case it eradicated the infection without interfere with the growth; neither epiphysiodesis nor other disorders were found during the follow-up. For the publication of this case report we followed the CARE guidelines for good clinical case reports; the parents gave consent for publication.

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