• Orthopaedic nursing · Jan 2011

    One statin, two statins, three statins, more: similarities and differences of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors.

    • Beatrice B Turkoski.
    • Graduate Faculty-Advanced Practice Nursing, Kent State University College of Nursing, Kent, OH, USA.
    • Orthop Nurs. 2011 Jan 1; 30 (1): 62-5; quiz 66-7.

    AbstractStatin drugs (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) are one of the most widely prescribed drugs today. They are considered first-line therapy to lower blood serum cholesterol levels in conjunction with therapeutic lifestyle changes for both primary and secondary prevention of cardiovascular events. In the following discussion, a brief explanation of the background of statins will explain why they are deemed so important today. The similarities and differences between the different statins will be addressed, including a look at dosage, side effects, and cautions for the seven 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors currently available.

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