• Internal medicine journal · Mar 2020

    Review

    New advances in the management of cytomegalovirus in allogeneic haemopoietic stem cell transplantation.

    • Michelle K Yong, David Gottlieb, Julian Lindsay, Jen Kok, William Rawlinson, Monica Slavin, David Ritchie, Ashish Bajel, and Andrew Grigg.
    • Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
    • Intern Med J. 2020 Mar 1; 50 (3): 277-284.

    AbstractCytomegalovirus (CMV) viraemia continues to be a frequent complication in the post-haemopoietic stem cell transplantation period despite a low incidence of CMV end-organ disease. Several significant advances in the understanding and management of CMV infection have occurred in the last few years including improved diagnostics, monitoring of CMV immunity, availability of novel anti-CMV drugs, and emerging use of immunotherapies including CMV-specific T-cell infusions. In addition to reviewing these advances we also explore some of the more practical prescribing issues of the older and newer CMV drugs including cost, toxicity and drug interactions to help clinicians navigate this new era of CMV management.© 2019 Royal Australasian College of Physicians.

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