• Internal medicine journal · Mar 2020

    Cancer-associated prothrombotic pathways: leucocytosis, but not thrombocytosis, correlates with venous thromboembolism in women with ovarian cancer.

    • Javier López-Salazar, Laura A Ramírez-Tirado, Nora Gómez-Contreras, Irlanda Pacheco-Bravo, Evelyn Cortés, Dolores Gallardo, Oscar Arrieta, and Gabriela Cesarman-Maus.
    • Department of Hematology, Instituto Nacional de Cancerología, Mexico City, Mexico.
    • Intern Med J. 2020 Mar 1; 50 (3): 366-370.

    AbstractRisk factors for venous thromboembolism in cancer vary between tumours. Leucocytosis, thrombocytosis, tumour histology and vascular compression may drive thrombosis in ovarian cancer. Thrombosis developed in 13.4% of our patients. Higher median leucocyte, neutrophil and monocyte counts were related to thrombosis. Thrombocytosis >350 × 109 /L was frequent (63.8%), but not predictive of thrombosis. Identification of prothrombotic biomarkers may help personalise preventive treatments.© 2020 Royal Australasian College of Physicians.

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