• C C A Grim, A D Cornet, A Kroner, A J Meiners, A J B W Brouwers, A C Reidinga, D J van Westerloo, Bergmans D C J J DCJJ Leiden University Medical Centre, Leiden, the Netherlands., D Gommers, D Versluis, D Weller, Christiaan Boerma E E Leiden University Medical Centre, Leiden, the Netherlands., E van Driel, E de Jonge, F J Schoonderbeek, H J F Helmerhorst, H G Jongsma-van Netten, J Weenink, K J Woittiez, K S Simons, L van Ewelie, M Petjak, M J Sigtermans, M van der Woude, O L Cremer, P Bijlstra, P van der Heiden, R K L So, R Vink, T Jansen, and W de Ruijter.
• Leiden University Medical Centre, Leiden, the Netherlands.
• Neth J Med. 2020 Jul 1; 78 (4): 167-174.

BackgroundOver the last decade, there has been an increasing awareness for the potential harm of the administration of too much oxygen. We aimed to describe self-reported attitudes towards oxygen therapy by clinicians from a large representative sample of intensive care units (ICUs) in the Netherlands.MethodsIn April 2019, 36 ICUs in the Netherlands were approached and asked to send out a questionnaire (59 questions) to their nursing and medical staff (ICU clinicians) eliciting self-reported behaviour and attitudes towards oxygen therapy in general and in specific ICU case scenarios.ResultsIn total, 1361 ICU clinicians (71% nurses, 24% physicians) from 28 ICUs returned the questionnaire. Of responding ICU clinicians, 64% considered oxygen-induced lung injury to be a major concern. The majority of respondents considered a partial pressure of oxygen (PaO2) of 6-10 kPa (45-75 mmHg) and an arterial saturation (SaO2) of 85-90% as acceptable for 15 minutes, and a PaO2 7-10 kPa (53-75 mmHg) and SaO2 90-95% as acceptable for 24-48 hours in an acute respiratory distress syndrome (ARDS) patient. In most case scenarios, respondents reported not to change the fraction of inspired oxygen (FiO2) if SaO2 was 90-95% or PaO2 was 12 kPa (90 mmHg).ConclusionA representative sample of ICU clinicians from the Netherlands were concerned about oxygen-induced lung injury, and reported that they preferred PaO2 and SaO2 targets in the lower physiological range and would adjust ventilation settings accordingly.

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