• Medicine · Apr 2019

    Meta Analysis

    Liuwei Dihuang Decoction for primary osteoporosis: A protocol for a systematic review and meta-analysis.

    • Yu Liu, Ping Wang, Xiuqun Shi, Huijin Li, Xionghui Zhang, Shenghu Zeng, Zhoufa Xu, Dongqing Lai, and Minling Zhang.
    • Department of Orthopaedics, Heyuan Hospital of Chinese Medicine.
    • Medicine (Baltimore). 2019 Apr 1; 98 (16): e15282e15282.

    BackgroundPrimary osteoporosis (POP) is one kind of global disease, as a serious threat to human health. Liuwei Dihuang Decoction (LWDHD) has been recommended to treat osteoporosis alone or combined with medicine in China; however, its efficacy is unclear. The object of this systematic review and meta-analysis is to evaluate the efficacy and safety of LWDHD in the management of POP.MethodsWe will search The Cochrane Library, Medline, PubMed, Elsevier, Springer, Web of Science, Ovid, WHO ICTRP, CNKI, CBM, VIP, and WanFang Database from their inception to February 2019. All randomized controlled trials (RCTs) of LWDHD for the treatment of POP will be included. The language is limited to Chinese and English. The fracture incidence will be accepted as the primary outcomes. Data synthesis, subgroup analysis, sensitivity analysis will be performed by using RevMan V.5.3.5 software.ResultsA high-quality synthesis of current evidence for the treatment of POP with LWDHD will be provided from efficacy and safety.ConclusionThis systematic review will generate evidence for judging whether LWDHD is an effective and safe intervention for POP or not.Prospero Registration NumberPROSPERO CRD 4201926066.

      Pubmed     Free full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…