• Suguru Hirose, Naoyuki Hasegawa, Hitomi Kawai, Masamichi Yamaura, Tsuneo Mizui, Yoshiki Komatsu, Masaomi Nagase, Masashi Sato, Junji Hattori, Masato Endo, Yoshiyuki Yamamoto, Kazunori Ishige, Kuniaki Fukuda, Ichinosuke Hyodo, and Yuji Mizokami.
• Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan.
• Intern. Med. 2020 Oct 15; 59 (20): 2505-2509.

AbstractA 70-year-old woman was referred to our department due to a solitary mediastinal tumor which gradually grew near the site of anastomosis for 8 years after radical surgery of esophageal squamous cell carcinoma. It was difficult to distinguish the lymph node recurrence of esophageal cancer from another tumor of unknown primary origin. Endoscopic ultrasound-guided fine-needle aspiration was performed, and the tumor was diagnosed to be neuroendocrine carcinoma. She received concurrent chemoradiotherapy with etoposide plus cisplatin. After the completion of chemoradiotherapy, the tumor disappeared. A solitary growing tumor which develops after radical resection of cancer would be better to be examined histologically in order to make an accurate diagnosis and select the most appropriate treatment.

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