ANCA-ASSOCIATED VASCULITIDES: RECOMMENDATIONS OF THE FRENCH

Presse Med · Oct 2020

Review Practice Guideline

ANCA-ASSOCIATED VASCULITIDES: RECOMMENDATIONS OF THE FRENCH VASCULITIS STUDY GROUP ON THE USE OF IMMUNOSUPPRESSANTS AND BIOTHERAPIES FOR REMISSION INDUCTION AND MAINTENANCE.

Treatment of vasculitides associated with anti-neutrophil cytoplasm antibodies (ANCA) (AAVs) has evolved dramatically in recent years, particularly since the demonstration of rituximab efficacy as remission induction and maintenance therapy for granulomatosis with polyangiitis and microscopic polyangiitis. In 2013, the French Vasculitis Study Group (FVSG) published recommendations for its use by clinicians. Since then, new data have made it possible to better specify and codify prescription of rituximab to treat AAVs. Herein, the FVSG Recommendations Committee, an expert panel comprised of physicians with extensive experience in the treatment and management of vasculitides, presents its consensus guidelines based on literature analysis, the results of prospective therapeutic trials and personal experience.

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- Benjamin Terrier, Pierre Charles, Olivier Aumaître, Alexandre Belot, Bernard Bonnotte, Yoann Crabol, Cécile-Audrey Durel, Mikael Ebbo, Noémie Jourde-Chiche, Jean-Christophe Lega, Xavier Puéchal, Grégory Pugnet, Thomas Quemeneur, Camillo Ribi, Maxime Samson, Frédéric Vandergheynst, Loïc Guillevin, and French Vasculitis Study Group.
- Service de médecine interne, hôpital Cochin, université Paris Descartes, Sorbonne Paris Cité, Paris, France; INSERM unité 1016, institut Cochin, Paris, France; Centre de référence pour les maladies auto-immunes rares, hôpital Cochin, Paris, France. Electronic address: benjamin.terrier@aphp.fr.
- Presse Med. 2020 Oct 1; 49 (3): 104031.
AbstractTreatment of vasculitides associated with anti-neutrophil cytoplasm antibodies (ANCA) (AAVs) has evolved dramatically in recent years, particularly since the demonstration of rituximab efficacy as remission induction and maintenance therapy for granulomatosis with polyangiitis and microscopic polyangiitis. In 2013, the French Vasculitis Study Group (FVSG) published recommendations for its use by clinicians. Since then, new data have made it possible to better specify and codify prescription of rituximab to treat AAVs. Herein, the FVSG Recommendations Committee, an expert panel comprised of physicians with extensive experience in the treatment and management of vasculitides, presents its consensus guidelines based on literature analysis, the results of prospective therapeutic trials and personal experience.Copyright © 2020 Elsevier Masson SAS. All rights reserved.

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ANCA-ASSOCIATED VASCULITIDES: RECOMMENDATIONS OF THE FRENCH VASCULITIS STUDY GROUP ON THE USE OF IMMUNOSUPPRESSANTS AND BIOTHERAPIES FOR REMISSION INDUCTION AND MAINTENANCE.

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