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Internal medicine journal · Jul 2020
Diabetes insipidus complicating apoplexy during pregnancy: the potential use of copeptin.
- Lisa K Bichard and David J Torpy.
- Adult Endocrinology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
- Intern Med J. 2020 Jul 1; 50 (7): 877-879.
AbstractPituitary apoplexy during pregnancy is rare but important to recognise, particularly in the hyperoestrogenaemic state when known lactotroph hyperplasia occurs. Untreated, the complication rates from pituitary adenomas depend upon the size of the adenoma before pregnancy. A history of thirst plus polydipsia during pregnancy raises suspicion for diabetes insipidus and a 24-h urine collection quantifying polyuria with an inappropriately low urine osmolality confirms the diagnosis. Further evaluation for assessing diabetes insipidus in pregnancy may be facilitated by the use of a copeptin.© 2020 Royal Australasian College of Physicians.
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